Single-step nanoparticle antigen presentation system for tumor immunotherapy
نویسندگان
چکیده
منابع مشابه
Single-step nanoparticle antigen presentation system for tumor immunotherapy
Background and aim While only 10-30% of patients treated with currently approved single immunotherapies demonstrate longterm benefit, treatment efficacy in responders correlates with increased CD8+ T cell responses to neoantigens (tumor antigens hidden from the immune system). Thus, to improve presentation of tumor antigens and expose neoantigens we engineered a single-step nanoparticle antigen...
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ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2015
ISSN: 2051-1426
DOI: 10.1186/2051-1426-3-s2-p319